Bactericidal Disinfection of Activated Carbon from Aerobic Microorganisms, Yeasts and Molds

One of the reasons for non-compliance with requirements regulatory documentation powdered materials, including drugs is microbiological contamination. The search alternative technical approaches bactericidal disinfection using modern physical methods relevant research. Checking compliance activated carbon «Silcarbon», which used in medicine as a sorbent, showed that number fungi (TYMS) exceeds permissible norms several times. A experimental studies where ultraviolet light, combination UV radiation and ozonation were have been performed to disinfect «Silcarbon» from contaminants. It shown optimal results can be achieved terms content molds yeasts: total amount does not exceed 70 CFU/g ozonation. When pulsed lamps flux density 10000-10500 W/m2, was 30 CFU/g, 20 meets documents. In dependance on method use contamination ranges 50 CFU/g.